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Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain

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Beschreibung
Peroxynitrite (ONOO-) plays a critical role in Alzheimer's disease (AD), and the association between ONOO- and AD is inexplicit. To reveal the ONOO- influxes in AD brains, an activatable activity-based fluorescence probe Rd-DPA3 was rationally designed by a structure-modulated strategy. Taking advantage of ONOO--sparked two-step cascade reactions of a novel chemical trigger, Rd-DPA3 specifica
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Activity-based fluorescence probes for pathophysiological
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Activity-based fluorescence probes for pathophysiological
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Small-molecule fluorescence-based probes for interrogating major
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
IJMS, Free Full-Text
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Scheme 2 Design strategy of probe 1 for the detection of
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Activatable fluorescent probes for imaging and diagnosis of
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Targets, Free Full-Text
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Activity-based fluorescence probes for pathophysiological
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Investigating New Applications of a Photoswitchable Fluorescent
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Targets, Free Full-Text
Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
Near-Infrared Fluorescent Probes as Imaging and Theranostic
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